About Help FAQ

Symbol
Name
ID

Tlr4
toll-like receptor 4
MGI:96824

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Anorexia	Meningitis	Ataxia	Depression	Irritability	Anxiety	Headache	Peripheral neuropathy	Seizure	Paresthesia
Disease(s) Associated with TLR4	Anorexia	Meningitis	Ataxia	Depression	Irritability	Anxiety	Headache	Peripheral neuropathy	Seizure	Paresthesia
Behcet's disease
familial mediterranean fever
temporal arteritis

Mouse Phenotypes

abnormal glial cell apoptosis

decreased neuron apoptosis

abnormal neuron differentiation

abnormal microglial cell physiology

decreased susceptibility to ischemic brain injury

decreased cerebral infarct size

abnormal nervous system morphology

abnormal myelin sheath morphology

abnormal retina rod bipolar cell morphology

abnormal retina rod cell morphology

abnormal glial cell physiology

brain ischemia

Availability

Mouse Genotype

Tlr4^Lps-d/Tlr4^Lps-d

Tlr4^lps-del/Tlr4^lps-del

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23